More than apical: distribution of SGLT1 in Caco-2 cells
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چکیده
منابع مشابه
More than apical: Distribution of SGLT1 in Caco-2 cells.
We investigated the distribution of the endogenous sodium-d-glucose cotransporter (SGLT1) in polarized Caco-2 cells, a model for enterocytes. A cellular organelle fraction was separated by free-flow electrophoresis and subjected to the analysis of endogenous and exogenous marker enzymes for various membrane vesicle components. Furthermore, the presence of SGLT1 was tested by an ELISA assay empl...
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THE UPTAKE OF GLUCOSE by the intestine is sodium dependent (4). The flow of glucose is accompanied by the movement of an equivalent number of sodium ions (14). There are at least three human forms of sodiumdependent glucose transporters: SGLT1, SGLT2, and SGLT3 (15). SGLT1 was cloned from rabbit intestine (9), and when this protein was expressed in Xenopus laevis oocytes, D-glucose uptake rates...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Cell Physiology
سال: 2003
ISSN: 0363-6143,1522-1563
DOI: 10.1152/ajpcell.00041.2003